Following on from revelations that we have a complex symbiotic relationship with our #gut microbiome, the discovery that we also have a #urobiome has attracted much attention. There’s no going back to believing the urinary #bladder is sterile. Thank you, Alan #Wolfe. Studies showing differences between normal and diseased bladder urobiomes raise questions about their influences on bladder health and disease aetiology, especially regarding #inflammatory and #pain syndromes,

From Prof. Scott Glickman: A GAG (#glycosaminoglycan) layer within the #bladder, as a nanometres-thick coating, surely would be less than 2ml. Why do companies sell costly GAG-layer supplements as 50ml treatments? I’ve been asking this question for years, but still await a plausible answer, let alone an evidence-based one. #bladderhealth

From our CMO Professor Scott Glickman Colleagues: In medical and surgical services spanning primary through intensive care, we are dogged by UTI with their acute and long-term complications: treatment failures, recurrences, urosepsis, antimicrobial resistance (AMR) and high costs. Despite continuous improvements in antibiotic stewardship, these problems show little sign of abating. Something else must be involved. Antibiotic overuse and misuse shouldn’t be blamed exclusively

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