Colleagues While I applaud last week’s publication of the Lancet Commission report on Dementia 2024 that provided updated information on...

The case for widening the #intravesical approach to #bladder diseases and disorders In the European Association of #Urology 2024 conference, intravesical chemotherapy “took centre stage:” https://www.linkedin.com/pulse/eau24-expert-commentary-professor-fufu-zheng-nmibc-postoperative-i6xre?trk=organization_guest_main-feed-card_feed-article-content The case for their use in uro-oncology was made over 60 years ago with the introduction of Mitiomycin C. The value in delivering d

I offer this “case report” and cautionary note to dedicated doctors with inventive minds. For many years in UK medicine, the most...

#Overactivebladder syndrome, (OAB), describing #urinaryurgency of unknown cause, was so named because #urodynamic investigations of...

This page from European Urology is enlightening for anyone treating urinary urgency or taking the treatments. The text explains that oral treatments’ beneficial responses are slight, modest and substantially placebo effects at the cost of over twice the risk of inducing cognitive impairments. They also produce symptomatic side effects, most notably dry mouth, that are real and mechanistically well understood as antimuscarinic actions on tissue receptors. The authors explain t