On the day of the UK’s launch of its new #AMR 5-year plan, I offer this account as it is closely linked in attempting to reduce the incidences of CAUTI, and thus, incident AMR risks. Here’s some food for thought Patients and health services suffer the scourge of CAUTI in both hospitals and communities. No approved strategy has made a substantial difference. Various alternatives exist but need unblocking by officialdom. Here’s a selection: 1 - #Catheter cleaning: To prevent

Unconscious bias is a systematic cognitive error in decision-making, about which the decision-maker is unaware. Unconscious bias against #bladders is common, especially infected ones. Compared to other organs, progress in #cystitis management has barely changed for ~ ¾ of a century, despite incidences increasing, recurrences abounding, and AMR becoming more pervasive, because of antiquated, flawed and haphazard treatments. We challenge “haphazard” through #antibioticsteward

#Epithelia line tissue surfaces that the outside world can directly access, such as skin, sclera, mouth, gut, vagina, #bladder and...

The distal urethra is a residency for #bacteria, mostly commensals, but sometimes potential uropathogens move in. #Catheterisation hygiene cleans the skin around the urethral meatus but does not remove bacteria residing in the distal urethra. Many people have focused time, effort and money on coatings that are supposed to prevent such bacteria surviving #catheter entry into the #bladder. Such a #coating would need to kill the potential pathogens before they are transferred fr

This page from European Urology is enlightening for anyone treating urinary urgency or taking the treatments. The text explains that oral treatments’ beneficial responses are slight, modest and substantially placebo effects at the cost of over twice the risk of inducing cognitive impairments. They also produce symptomatic side effects, most notably dry mouth, that are real and mechanistically well understood as antimuscarinic actions on tissue receptors. The authors explain t